BUFFALO, N.Y. — Have you heard the saying “gut brain?” It’s a real thing. Research is showing how nutrient deficiency is impacting mental health.
Here are the 16 top essential nutrients for brain health for both adults and kids, according to psychiatric nurse practitioner Daniel Breeyear.
Omega-3 Fatty Acids (DHA, EPA)
- Role: Crucial for brain structure, synaptic plasticity and reducing inflammation
- Sources: Fatty fish (salmon, sardines), flaxseed, walnuts, algae oil
Iron
- Role: Required for oxygen transport and dopamine synthesis; deficiency linked to poor focus and fatigue
- Sources: Red meat, spinach, lentils, fortified cereals
Zinc
- Role: Neurotransmitter function, synaptic plasticity and learning
- Sources: Pumpkin seeds, beef, chickpeas
Magnesium
- Role: Calms the nervous system, regulates GABA, prevents overstimulation
- Sources: Leafy greens, almonds, dark chocolate, legumes
Vitamin B6
- Role: Cofactor in serotonin, dopamine, GABA synthesis
- Sources: Bananas, poultry, fortified cereals
Vitamin B12
- Role: Protects nerves, supports methylation and neurotransmitters
- Sources: Meat, dairy, eggs, fortified plant milks
Folate (B9)
- Role: Critical for DNA synthesis, methylation and serotonin regulation
- Sources: Leafy greens, beans, liver, avocados
Vitamin D
- Role: Regulates mood, immune system, and may protect against depression and neurodevelopmental disorders
- Sources: Sunlight, fatty fish, fortified dairy or plant milks
Choline
- Role: Builds acetylcholine for memory and attention, especially critical in pregnancy and early childhood
- Sources: Eggs (especially yolks), liver, soybeans
Iodine
- Role: Supports thyroid hormones, which are essential for brain development
- Sources: Iodized salt, seaweed, dairy
Selenium
- Role: Antioxidant function and thyroid regulation
- Sources: Brazil nuts, tuna, whole grains
Chromium
- Role: Enhances insulin sensitivity, stabilizing blood sugar for cognitive energy
- Sources: Broccoli, grape juice, whole grains, green beans
Manganese
- Role: Antioxidant enzyme (MnSOD), supports mitochondria and neurotransmitter synthesis
- Sources: Whole grains, nuts, leafy greens
Calcium
- Role: Supports neurotransmitter release, muscle contraction, and synaptic plasticity
- Sources: Dairy, fortified plant milks, leafy greens
Phosphorus
- Role: Essential for cell membrane structure, energy production (ATP), and cognitive function
- Sources: Dairy, meat, legumes, whole grains
Copper
- Role: Supports neurotransmitter synthesis and antioxidant function; protects brain cells
- Sources: Shellfish, nuts, seeds, dark chocolate
Not having enough of these make us feel tired, irritable, show signs of ADHD, makes it tough to learn, causes poor focus and prevents overstimulation, according to Breeyear. He started studying and learning about the gut to brain connection during the COVID-19 pandemic. He breaks it down like this: First stress causes inflammation. Inflammation causes inhibition of neurotransmitters to be creative at adequate levels. He says therapy is great because it teaches people how to manage that stress.
But there’s more to it. It starts with looking at labels, then staying away from high processed foods. Breeyear says the further away we get from the ground, the air and the sea, the higher the inflammation levels. We are on what’s known as the SAD diet — the standard American diet. Our best way to combat that, he says, is education.
“It seems new and complex to people, but it’s really as simple as it gets,” Breeyear said. “You know, your body, your brain and nature are smarter than you are. We just think we just don’t realize that sometimes. So the things that you know, that are created naturally are really what we’re designed to mean.”
He says don’t discount vitamin D, especially upstate. It regulates mood, immune system, and may protect against depression and neurodevelopmental disorders. Madvash Madni is a pediatrician. She says this should be a whole family thing. It goes back to setting up that dinner plate masterpiece we’re taught as kids.
“Half of it is fruits and vegetables, lots of colors and lots of greens and, a quarter of it,” Madni said, “you want to have your protein. The animal proteins are the best to get, you know, the B vitamins and the iron and zinc, then the whole grain. not the refined grains, and then there should be some dairy.”
Madni says for picky eaters, get them involved in the meal-making process and offer choices. She adds you don’t have to give up junk food, but just make a one day a week special treat.
Healthy foods, though, can be expensive. Don’t discount frozen fruits and veggies, especially if you buy in bulk. Also, make sure you’re portioning correctly.
Here are some common nutrient deficiencies that Breeyear says are linked to mental health symptoms:
- Iron deficiency – brain fog, fatigue, ADHD-like symptoms
- Vitamin D deficiency – low mood, increased anxiety, seasonal affective symptoms
- Omega-3 deficiency – impulsivity, poor emotional regulation
- Magnesium deficiency – insomnia, irritability, restlessness
- B vitamin deficiencies – mood instability, memory problems, apathy
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